We’re officially through two weeks of the NFL season and the injuries are already piling up. San Francisco 49ers superstar Christian McCaffrey was placed on injured reserve with Achilles tendinitis, Kansas City Chiefs running back Isiah Pacheco will miss time with a fractured fibula, and the Los Angeles Rams are running out of wide receivers. 

Here’s a list of the most significant players dealing with injuries and their latest statuses ahead of Week 3.