The 15th-century explorer Christopher Columbus was a Sephardic Jew from Western Europe, Spanish scientists said on Saturday, after using DNA analysis to tackle a centuries-old mystery.

Several countries have argued over the origins and the final burial place of the divisive figure who led Spanish-funded expeditions from the 1490s onward, opening the way for the European conquest of the Americas.

Many historians have questioned the traditional theory that Columbus came from Genoa, Italy. Other…